Vall d'Hebron Talks by VHIR 'Biomarkers in MS: from CSF to blood'

 Vall d'Hebron Talks by VHIR
  Sala d’actes de la planta baixa de l’Hospital General — See in map
27/02/2024
27/02/2024 -- From 15:00h to 16:00h
Organize :
Vall d'Hebron Institut de Recerca (VHIR)
Modality: Presencial i en línia
Share it:

Speaker: Dr. Nicolás Fissolo, is senior investigator at the Centre d’Esclerosi Multiple de Catalunya (Cemcat) at the Vall d'Hebron University Hospital in Barcelona.
He graduated with a degree in biological chemistry at the University of Córdoba, Argentina in 1999. In 2005, he obtained a Ph.D. in human biology from the University of Ulm, Germany for his work in the DNA vaccine field. Afterwards he carried out a 3-year postdoctoral stage at the Hertie Institute for Clinical Brain Research, in Tübingen, Germany focused in the study of antigen presentation in MS. In 2008, he joined the group of Xavier Montalban, at the Institut de Recerca, Hospital Vall d’Hebron in Barcelona where he is currently working.

Abstract: In the context of multiple sclerosis (MS), the need for objective and measurable indicators of the underlying pathological processes is critical to predict response, disease progression, prognosis and outcome of disease. Therefore, the search for biomarkers, is a continuously expanding field, and a large number of molecules have been explored so far; but only a few have been validated, and even fewer are currently used in clinical practice. 
In neurological disorders like MS, because of its close proximity to the target organ, the cerebrospinal fluid (CSF) will probably capture better the pathological changes taking place in the central nervous system of MS patients. However, due to the difficulties to access to longitudinal CSF samples to follow-up patient’s progression, it should investigate whether the CSF biomarker is also detected in peripheral blood, serum or plasma, and whether the differences observed in protein abundance in the CSF are also present in blood. In this presentation we will discuss the role of different biomarkers in patients with MS, and we will talk about the transition from CSF to blood guided by the evolution of technologies for biomarker detection.

Host: Dr. Manuel Comabella López, main researcher, group Clinical Neuroimmunology at Vall d’Hebron Research Institute (VHIR)

Register here to attend by Zoom: https://gencat.zoom.us/j/95396181541

Related activities

Introducción a la hidrocefalia y alteraciones de la dinámica de LCR

09/02/2024 - 09:00
More information

XIX Curso teórico-práctico de Ecocardiografía básica y avanzada en medicina de urgencias, intensiva y anestesia

09/16/2024 - 09:00
Cardiología, Medicina Intensiva, Anestesia y Reanimación, Neurología
More information

Fundamentos fisiopatológicos de la hipoxia tisular y monitorización del aporte cerebral de oxígeno

09/30/2024 - 09:00
Facultativos especialistas, residentes y personal de enfermería interesados ​​en el manejo del paciente neurocrítico
More information

II Curso CARE ME

10/03/2024 - 08:45
Cardiología y Nefrología
More information

Subscribe to our newsletters and be a part of Campus Life

Select the newsletter you want to receive:

By accepting these conditions, you are agreeing to the processing of your personal data for the provision of the services requested through this portal, and, if necessary, for any procedures required by the administrations or public bodies involved in this processing, and their subsequent inclusion in the aforementioned automated file. You may exercise your rights to access, rectification, cancellation or opposition by writing to web@vallhebron.cat, clearly stating the subject as "Exercising of Data Protection Rights".
Operated by: Hospital Universitari Vall d'Hebron - Institut Català de la Salut.
Purpose: Manage the user’s contact information.
Legitimisation: Express acceptance of the privacy policy.
Rights: To access, rectify, and delete personal information data, as well to the portability thereof and to limit and/or oppose their use.
Source: The interested party themselves.