We are the combination of four hospitals: the General Hospital, the Children’s Hospital, the Women’s Hospital and the Traumatology, Rehabilitation and Burns Hospital. We are part of the Vall d’Hebron Barcelona Hospital Campus: a world-leading health park where healthcare plays a crucial role.
Below we will list the departments and units that form part of Vall d’Hebron Hospital and the main diseases that we treat. We will also make recommendations based on advice backed up by scientific evidence that has been shown to be effective in guaranteeing well-being and quality of life.
Vols saber com serà la teva estada a l’Hospital Universitari Vall d’Hebron? Aquí trobaràs tota la informació.
Speaker: Octavio Alfredo Romero Ferraro, principal investigator cancer epigenetics and Biology Program - Josep Carreras Research Institute (IJC)
In Pediatric cancer, the traditional cytotoxic therapeutic approaches are always a compromise between treatment efficacy and the risk of developing severe secondary effects, including new tumours during the adulthood. Our previous study demonstrates that SMARCA4 is necessary to regulate the demethylase activity of H3K27me3 in cancer, we discover that the inhibition of KDM6A/B is lethal specifically in SMARCA4 deficient tumors. This discovery implicates a new synthetic lethality, in which inactivating mutations in SWI/SNF members could sensitize cancer cells to specific epigenetic inhibitors affecting pediatric tumours.
Host: Miguel Segura Ginard, main researcher Childhood Cancer and Blood Disorders (VHIR)
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