Osteogenesis imperfecta

Osteogenesis imperfecta (OI), also known as "brittle bone disease", is a genetic disorder that affects the production of collagen, a principal element in connective tissue and bone. These individuals easily sustain fractures, even without trauma. There are various types of OI, so symptoms can vary. In most cases, the disease is caused by a mutation in the gene coding for type I collagen.

Authorship: Vall d'Hebron
Creation date: 14.03.2022, 10:06
Modification date: 01.12.2022, 11:18
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