Paget's disease

This is the second most frequent bone disorder, following osteoporosis.  It affects 1.5-3% of the population over 65 years of age. It was described by Sir James Paget in 1876. In this disease, the natural process of the destruction of old bone and the formation of new bone (called bone remodelling) is abnormal and disordered. As a consequence, the bone is fragile, it increases in size, and it presents deformity. Thus, it also receives the name of deforming osteitis. It usually affects the cranium, spinal column, and the pelvis. The risk of having this disease increases with age, and it is very rare in young people.

Authorship: Vall d'Hebron
Creation date: 14.03.2022, 09:23
Modification date: 01.12.2022, 11:17
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