What are you looking for? Search Common searches: Departments, Hospitalisation, Professionals, Outpatient clinics, Health advice, Accreditations, Diseases, Diagnostic tests, Treatments, The birth of a child, Emergency, Visiting patients, Fulltext search Tipus de contingut Services and units Professionals Pathologies Health advices Health and wellness Diagnostic tests Treatments News Activities Centers - Any - Search Research groups Tumour Biomarkers We are looking for therapeutic targets and secretory tumour biomarkers based on signal transduction systems, using quantitative proteome methods. They also characterise the influence of non-classical secretion during tumour formation, especially in tumour invasion and metastasis. Research groups Gene Expression and Cancer By studying intratumoural heterogeneity, we are working to better understand the molecular mechanisms involved in cancer stem cells/stem cells. Developing methods for non-invasive molecular diagnosis by studying circulating biomarkers, and creating brain tumour models derived from patients in rat Research groups Stem Cells and Cancer The group’s strategic working lines are describing the key molecular mechanisms responsible for the self regeneration of stem cells in colon cancer (CoCSC); identifying the main molecules responsible for metastasis development in colon cancer. As well as determining the importance of new transcri Research groups Breast Cancer and Melanoma Among the group’s current objectives is putting into practice tumour sequencing in patients with breast cancer. We are studying the efficacy of PI3K/mTOR inhibitors and their relationship with mutational state, as well as continuing research on the factors involved in resistance to HER2 treatment Research groups Early Clinical Development of Drugs The Early Clinical Development of Drugs group promotes the early development of medicines and translational research through assessment and treatment of patients in phase I trials. They work on preliminary trials for targeted treatments aimed at cell signalling and cancer stem cells. They are als Research groups Gynaecological Neoplasia The work of the Gynaecological Neoplasia research group contributes to the early clinical development of drugs against gynaecological cancers, while also seeking to consolidate a translational research programme to advance precision medicine. Research groups Thoracic Tumours and Head and Neck Cancer The group is currently focusing on putting into practice ALK translocation, studying how effective PI3K/mTOR inhibitors are in patients with EGFR-TKI-resistant lung cancer, and studying how effective PARP inhibitors are in lung cancer. They are analysing the epidemiological and clinical ch Research groups Genitourinary Tumours of the CNS and Sarcoma Currently, the group is focusing on designing and developing clinical trials for malignant genitourinary tumours with the active participation of researchers in the Urology, Radiotherapy and Medical Oncology departments. They are advancing in their research with the help of platforms creat Research groups High Risk and Prevention in Cancer Among its objectives are to promote the clinical development of specific therapeutic strategies for tumours associated with hereditary genetic alterations, and to identify the mechanisms of resistance to treatments for breast cancer associated with the BRCA gene. They evaluate new treatment combi Research groups Oncogenetics The group is currently focusing on identifying new ovarian and breast cancer susceptibility genes through massive sequencing (sets of exomes and genes) and genome-wide association studies. The functional characterisation and expression of variants of unknown clinical importance in genes that pred Pagination Previous page ‹‹ Page 48 Next page ››