Vall d'Hebron Talks by VHIR 'ADHD prediction and comorbidities: a genetic/omics approach'

Speaker: Dr. María Soler Artigas, is a main researcher Psychiatry, Mental Health and Addictions in Vall d'Hebron Research Institute (VHIR)

Abstract: Attention Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental disorder characterized by a persistent pattern of inattentive, hyperactive, and impulsive behaviors, which increases the risk of health problems, psychiatric co-morbidities, social disability, academic and occupational failure, and risk behaviours throughout the individual’s life. ADHD is highly heritable, although a large proportion of its heritability still needs to be explained. Gene expression, which results from the interplay between genetic and environmental factors, may help to elucidate additional phenotypic variance. In addition, most of its comorbidities are also highly heritable, with genetic risk factors being involved not only in their individual etiology but also in their co-occurrence. 

This presentation will focus on a genetic approach to elucidate causal relationships between two traits, Mendelian randomization, and its application to ADHD and co-occurring traits and will also show the results of a study which integrates genetic and gene expression data to improve prediction of ADHD.

Host: Dr. Marta Ribasés Haro, Main researcher Psychiatry, Mental Health and Addictions in Vall d'Hebron Research Institute (VHIR)

Registre Online: https://gencat.zoom.us/j/94627693882